Skip to main content
. 2021 Apr 20;9:672267. doi: 10.3389/fchem.2021.672267

Figure 5.

Figure 5

Trans-photoPROTAC and cis-photoPROTAC. trans-photoPROTAC displays an optimal distance between both warhead moieties to engage the proteins in a ternary complex; in red is shown the “pull-pull” diacid linker. cis-photoPROTAC is shorter and thus inactive (Pfaff et al., 2019).