Table 3.
Effects of repetitive treatments with PNEO on biochemical parameters.
| Parameter | Treatment |
|||
|---|---|---|---|---|
| Control | PNEO |
|||
| (5 mg/kg) | (10 mg/kg) | (50 mg/kg) | ||
| AST (U/L) | 94.6 ± 5.5 | 88.5 ± 4.4 | 101.3 ± 6.7 | 98.2 ± 6.3 |
| ALP (U/L) | 64.5 ± 6.1 | 72.2 ± 7.6 | 64.3 ± 4.5 | 75.6 ± 5.5 |
| ALT(U/L) | 51.4 ± 3.4 | 54.4 ± 6.1 | 58.6 ± 6.4 | 55.5 ± 4.2 |
| Glucose (mg/dl) | 254 ± 16.3 | 234.5 ± 14.7 | 221.6 ± 15.2 | 232 ± 15.6 |
| Urea (mg/dl) | 42.6 ± 4.7 | 48.2 ± 5.1 | 45.6 ± 6.2 | 40.8 ± 5.5 |
| Creatinine (mg/dl) | 0.56 ± 0.08 | 0.51 ± 0.04 | 0.48 ± 0.06 | 0.52 ± 0.04 |
| Triglycerides (mg/dl) | 94.6 ± 6.4 | 96.8 ± 4.4 | 76.5 ± 5.4 | 72.2 ± 3.8 |
| Total cholesterol (mg/dl) | 78.5 ± 5.5 | 66.64 ± 2.4 | 49.3 ± 3.8∗ | 44.6 ± 4.6∗ |
The animal were treated with vehicle (control), PNEO (5, 10 and 50 mg/kg, p.o.). Data are represented as mean ± SEM (n = 6) and the values obtained by comparison with control group using one-way ANOVA followed by Dunnett's test, Where ∗ indicates p < 0.05.