Table 1.
Demographics and perfusion imaging data for the full cohort and patient subgroups
| Variable | Full cohort (n=92) | Alive (n=78) | Dead (n=14) | P value |
|---|---|---|---|---|
| Preprocedural variables | ||||
| Age (years) (mean±SD) | 68.8±13.5 | 67.0±13.3 | 79.0±9.6 | 0.002 |
| Male sex (n (%)) | 46 (50.0) | 41 (52.6) | 5 (35.7) | 0.246 |
| Caucasian race (n (%)) | 78 (84.8) | 67 (85.9) | 11 (78.6) | 0.482 |
| Minutes from LKN to groin puncture (mean±SD) | 676.1±147.7 | 678.2±153.0 | 664.4±118.4 | 0.750 |
| Median NIHSS score (IQR) | 16 (10–20) | 15 (9–19) | 20 (14–22) | 0.044 |
| Wake-up stroke (n (%)) | 49 (53.3) | 38 (48.7) | 11 (78.6) | 0.039 |
| Hypertension (n (%)) | 71 (77.2) | 60 (76.9) | 11 (78.6) | 0.892 |
| Diabetes (n (%)) | 28 (30.4) | 21 (26.9) | 7 (50.0) | 0.084 |
| Atrial fibrillation (n (%)) | 50 (34.5) | 28 (32.9) | 22 (36.7) | 0.642 |
| History of myocardial infarction (n (%)) | 12 (13.0) | 11 (14.1) | 1 (7.1) | 0.476 |
| History of statin use (n (%)) | 44 (47.8) | 34 (43.6) | 10 (71.4) | 0.055 |
| History of antiplatelet use (n (%)) | 41 (44.6) | 34 (43.6) | 7 (50.0) | 0.657 |
| History of anticoagulant use (n (%)) | 11 (12.0) | 8 (10.3) | 3 (21.4) | 0.235 |
| Lesion volume (mL) (mean±SD) | 15.4±17.0 | 15.2±15.9 | 16.5±22.9 | 0.792 |
| Hypoperfused volume (mL) (mean±SD) | 111.5±56.2 | 110.3±55.4 | 117.8±62.3 | 0.650 |
| Randomization systolic blood pressure (mean±SD) | 145.6±23.0 | 146.6±23.5 | 140.1±20.1 | 0.339 |
| Randomization diastolic blood pressure (mean±SD) | 78.5±15.1 | 79.1±15.5 | 75.4±12.5 | 0.393 |
| Postprocedural variables | ||||
| Revascularization (thrombolysis in cerebral infarction score ≥2 b) (n (%)) | 70 (76.1) | 61 (78.2) | 9 (64.3) | 0.261 |
| Symptomatic intracranial hemorrhage within 36 hours (n (%)) | 6 (6.5) | 1 (1.3) | 5 (35.7) | <0.001 |
| Lesion volume at 24 hours (mL) (n=90) (mean±SD) | 69.0±86.6 | 58.8±66.1 | 135.4±156.7 | 0.004 |
IQR, interquartile range; LKN, last known normal; NIH, National Institutes of Health Stroke Scale.