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‘Add-on’ approaches to ruxolitinib being studied in clinical trials.
| Agent (class) | Drug class | Phase (NCT number) | Reference |
|---|---|---|---|
| CPI-0610 | BET inhibitor | 2 (NCT02158858) | Mascarenhas et al. [70] |
| Navitoclax | BCL-2/BCL-xL antagonist | 2 (NCT03222609) | Harrison et al. [71] |
| Umbralisib | PI3Kδ inhibitor | 1 (NCT02493530) | Moyo et al. [76] |
| Parsaclisib | PI3Kδ inhibitor | 2 (NCT02718300) | Daver et al. [77] |
| Idelalisib | PI3Kδ inhibitor | 1 (NCT02436135) | - |
