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. 2021 May 3;4(5):e216831. doi: 10.1001/jamanetworkopen.2021.6831

Table 1. Background Characteristics of Girls by Puberty Onset in Rural Western China (N = 294)a.

Characteristic All (N = 294) Onset of puberty
Yes (n = 241) No (n = 53)
Parental during pregnancy
Maternal age, mean (SD), y 23.43 (4.09) 23.51 (4.12) 23.08 (3.97)
Maternal educational attainment
<3 y 12 (4.1) 7 (58.3) 5 (41.7)
Primary 59 (20.1) 50 (84.7) 9 (15.3)
Secondary 168 (57.3) 139 (82.7) 29 (17.3)
High school or higher 54 (18.4) 45 (83.3) 9 (16.7)
Maternal occupation
Farmer 237 (80.9) 194 (81.9) 43 (18.1)
Other 56 (19.1) 46 (82.1) 10 (17.9)
Parity
0 231 (78.6) 186 (80.5) 45 (19.5)
1 49 (16.7) 43 (87.8) 6 (12.2)
≥2 14 (4.8) 12 (85.7) 2 (14.3)
Maternal age at menarche, mean (SD), y 15.23 (1.37) 15.17 (1.39) 15.46 (1.26)
Maternal BMI, mean (SD) 20.56 (2.04) 20.57 (2.04) 20.50 (2.03)
Supplement regimen
Folic acid 99 (33.7) 76 (76.8) 23 (23.2)
Iron and folic acid 94 (32.0) 78 (83.0) 16 (17.0)
Multiple micronutrients 101 (34.4) 87 (86.1) 14 (13.9)
Paternal age, mean (SD), y 26.71 (3.96) 26.73 (4.07) 26.58 (3.42)
Paternal educational attainment
<3 y 3 (1.0) 3 (100) 0
Primary 21 (7.1) 19 (90.5) 2 (9.5)
Secondary 190 (64.6) 150 (78.9) 40 (21.1)
High school or higher 80 (27.2) 69 (86.3) 11 (13.8)
Paternal occupation
Farmer 207 (70.5) 172 (83.1) 35 (16.9)
Other 87 (29.6) 69 (79.3) 18 (20.7)
Household wealth index
Low 71 (24.1) 59 (83.1) 12 (16.9)
Middle 110 (37.4) 82 (74.5) 28 (25.5)
High 113 (38.4) 100 (88.5) 13 (11.5)
Infant at birth
Birth weight, mean (SD), g 3094 (380) 3112 (368) 3013 (426)
Birth length, mean (SD), cm 48.9 (2.3) 48.9 (2.3) 48.7 (2.3)
Gestational age at delivery, mean (SD), wk 40 (1) 40 (1) 40 (2)
SGA (<10th population percentile)
No 236 (82.5) 198 (83.9) 38 (16.1)
Yes 50 (17.5) 37 (74.0) 13 (26.0)
LBW (<2500 g)
No 279 (95.2) 230 (82.4) 49 (17.6)
Yes 14 (4.8) 10 (71.4) 4 (28.6)
Preterm birth (<37 wk)
No 287 (97.6) 235 (81.9) 52 (18.1)
Yes 7 (2.4) 6 (85.7) 1 (14.3)
Infant at 12 mo
WAZ, mean (SD) 0.33 (0.87) 0.44 (0.81) −0.19 (0.95)
Underweight (WAZ < −1.00 SD)
No 245 (93.2) 207 (84.5) 38 (15.5)
Yes 18 (6.8) 9 (50.0) 9 (50.0)
LAZ, mean (SD) −0.58 (0.96) −0.48 (0.92) −1.03 (1.03)
Stunting (LAZ < −2.00 SD)
No 247 (93.9) 208 (84.2) 39 (15.8)
Yes 16 (6.1) 8 (50.0) 8 (50.0)
BAZ, mean (SD) 0.92 (1.06) 1.00 (1.04) 0.57 (1.12)
Overweight (BAZ >2.00 SD)
No 222 (84.7) 182 (82.0) 40 (18.0)
Yes 40 (15.3) 34 (85.0) 6 (15.0)
Child at 24 mo
WAZ, mean (SD) 0.18 (0.80) 0.25 (0.78) −0.19 (0.85)
Underweight (WAZ < −1.00 SD)
No 236 (92.2) 200 (84.7) 36 (15.3)
Yes 20 (7.8) 12 (60.0) 8 (40.0)
LAZ, mean (SD) −0.89 (0.93) −0.80 (0.91) −1.33 (0.90)
Stunting (LAZ < −2.00 SD)
No 228 (88.7) 195 (85.5) 33 (14.5)
Yes 29 (11.3) 19 (65.5) 10 (34.5)
BAZ, mean (SD) 1.00 (1.00) 1.02 (0.97) 0.86 (1.13)
Overweight (BAZ >2.00 SD)
No 218 (85.5) 181 (83.0) 37 (17.0)
Yes 37 (14.5) 31 (83.8) 6 (16.2)
Early adolescence
Age, mean (SD), y 11.25 (0.57) 11.30 (0.58) 11.04 (0.48)
HAZ, mean (SD) 0.11 (1.03) 0.30 (0.97) −0.74 (0.83)
Stunting (HAZ < −2.00 SD)
No 285 (97.3) 237 (83.2) 48 (16.8)
Yes 8 (2.7) 3 (37.5) 5 (62.5)
BAZ, mean (SD) −0.39 (1.09) −0.19 (1.00) −1.29 (1.03)
Thinness (BAZ < −2.00 SD)
No 268 (92.7) 227 (84.7) 41 (15.3)
Yes 21 (7.3) 9 (42.9) 12 (57.1)

Abbreviations: BAZ, BMI-for-age z score; BMI, body mass index (calculated as weight in kilograms divided by square of height in meters); HAZ, height-for-age z score; LAZ, length-for-age z score; LBW, low birth weight; SGA, small for gestational age; WAZ, weight-for-age z score.

a

Unless otherwise indicated, data are expressed as No. (%) of patients. Data are missing for maternal educational attainment (n = 1), occupation (n = 1), age at menarche (n = 6), and BMI (n = 8); at birth, infant birth weight (n = 1), birth length (n = 17), SGA (n = 8), and LBW (n = 1); at 12 months of age, WAZ (n = 31), underweight (n = 31), LAZ (n = 31), stunting (n = 31), BAZ (n = 32), and overweight (n = 32); at 24 months of age, WAZ (n = 38), underweight (n = 38), LAZ (n = 37), stunting (n = 37), BAZ (n = 39), and overweight (n = 39); and in early adolescence, HAZ (n = 1), stunting (n = 1), BAZ (n = 5), and thinness (n = 5).