Table 2.
Cytotoxicity and mutagenicity in mouse lymphoma cells treated with Aloe veraa
| WLE | WLD | |||
|---|---|---|---|---|
| Dose (mg ml−1) | Relative total growth (%) | Mutant frequency (×10−6) | Relative total growth (%) | Mutant frequency (×10−6) |
| 0 | 100 ± 12 | 111 ± 12 | 100 ± 13 | 101 ± 13 |
| 3.0 | 105 ± 24 | 191 ± 36 | 107 ± 8 | 130 ± 22 |
| 3.5 | 92 ± 24 | 230 ± 52 | 99 ± 13 | 144 ± 9 |
| 4.0 | 82 ± 32 | 266 ± 110b | 87 ± 15 | 136 ± 26 |
| 4.5 | 57 ± 25 | 351 ± 175b | 69 ± 17 | 162 ± 13 |
| 5.0 | 42 ± 24 | 450 ± 183b | 60 ± 9 | 197 ± 21 |
| 6.0 | 28 ± 12 | 290 ± 195b | ||
| 7.0 | 21 ± 8 | 414 ± 253b | ||
| 8.0 | 16 ± 7 | 592 ± 364b | ||
a
The data points represent the mean ± SD of 4–5 independent experiments.
b
Positive response in the MLA, exceeding the global evaluation factor of 126 × 10−6.