Fig. 6.

Differences in intratumor stromal compartment of liver metastasis in sICAM-1- and CLX-treated mice. The infiltration of ASMA- and F4/80-expressing cells was quantified in the metastatic foci of mice under different treatment routines (A, B). Furthermore, the accumulation of intratumoral fibrillar collagen was analyzed (C) (n=6). Differences between the untreated C26 versus sICAM-1-treated C26 cell intratumoral expression of ASMA, F4/80, and collagen were considered statistically significant for *p<0.05. Differences between CLX-untreated versus CLX-treated animals were considered significant at ^#p<0.05 and ^##p<0.01 using Student’s t-test.