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. 2021 Jan 11;29(3):282–289. doi: 10.4062/biomolther.2020.201

Fig. 1.

Fig. 1

The structure of SARS-CoV-2 fusion core and sequence of peptides. (A) Schematic representation of SARS-CoV-2 Spike. The S1 subunit contains the N-terminal domain (NTD) and the receptor-binding domain (RBD). The S2 subunit comprises the fusion protein (FP) and two heptad repeat domains, HR1 and HR2. (B) HR1 and HR2 monomers during the fusion state showing the regions comprising the synthesized. (C) The position of peptides #1 and 2 on HR2. The side chains of amino acids is presented in green dots. (D) The sequences of peptides #1-12, the conserved sequences were highlighted with the same colour.