Study	Reason for exclusion
Aramideh 1995	Not randomised
Boyle 2009	No placebo group
Fahn 1985	Unclear if this was a randomised trial or not. Primary outcome was neurophysiological
Frueh 1988	It enrolled 26 participants with blepharospasm in a randomised, double‐blind trial comparing BtA to placebo. All participants received BtA in the upper eyelids and only the lower eyelids were randomised to BtA or placebo. It was not possible to compare BtA versus placebo
Girlanda 1996	Unclear if this was a randomised trial or not. Primary outcome was neurophysiological
Iwashige 1995	No placebo group
Jankovic 1987	Participants were randomised by a toss of a coin to BtA or placebo. Although 12 participants had blepharospasm, only 3 of them did not have additional involuntary movements of the face or neck. Ineligible population
Jankovic 1995	Not randomised. No placebo group
Mezaki 1995	No placebo group
Mezaki 1999	No placebo group
Nussgens 1997	No placebo group
Pagan 2018	Duplicate of Mitsikostas 2018
Park 1993	Only 4 participants with blepharospasm were enrolled in the blinded controlled phase. The report gave no clear data comparing the BtA and placebo groups containing these 4 participants. No usable study data
Price 1997	No placebo group
Sampaio 1997	No placebo group