Aramideh 1995 |
Not randomised |
Boyle 2009 |
No placebo group |
Fahn 1985 |
Unclear if this was a randomised trial or not. Primary outcome was neurophysiological |
Frueh 1988 |
It enrolled 26 participants with blepharospasm in a randomised, double‐blind trial comparing BtA to placebo. All participants received BtA in the upper eyelids and only the lower eyelids were randomised to BtA or placebo. It was not possible to compare BtA versus placebo |
Girlanda 1996 |
Unclear if this was a randomised trial or not. Primary outcome was neurophysiological |
Iwashige 1995 |
No placebo group |
Jankovic 1987 |
Participants were randomised by a toss of a coin to BtA or placebo. Although 12 participants had blepharospasm, only 3 of them did not have additional involuntary movements of the face or neck. Ineligible population |
Jankovic 1995 |
Not randomised. No placebo group |
Mezaki 1995 |
No placebo group |
Mezaki 1999 |
No placebo group |
Nussgens 1997 |
No placebo group |
Pagan 2018 |
Duplicate of Mitsikostas 2018
|
Park 1993 |
Only 4 participants with blepharospasm were enrolled in the blinded controlled phase. The report gave no clear data comparing the BtA and placebo groups containing these 4 participants. No usable study data |
Price 1997 |
No placebo group |
Sampaio 1997 |
No placebo group |