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. 2005 Jul 20;2005(3):CD003178. doi: 10.1002/14651858.CD003178.pub3

Kramer 1996.

Study characteristics
Methods open label, randomized cross‐over, intention to treat
Participants 8 patients with
congestive heart failure, class II‐III 
Age: 44‐65
Male: 7, Female: 1
Interventions Torsemide
Continuous: loading dose of 25 mg then 75 mg x 24 hours (3.125 mg/hour)
Bolus: 100 mg intravenously
Outcomes Urine output, sodium excretion at 24 hours
Notes Selection Bias: B
Performance Bias: B
Exclusion Bias: A
Detection Bias: B
Overall score: B
Risk of bias
Bias Authors' judgement Support for judgement
Allocation concealment (selection bias) Unclear risk B ‐ Unclear