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. 2021 Mar 30;2021(3):CD009098. doi: 10.1002/14651858.CD009098.pub3
Date Event Description
12 June 2020 New citation required but conclusions have not changed In this review, we have made certain changes with respect to the previous review: we have excluded studies with no difference in the levels of PEEP between groups being compared, and we have performed subgroup analyses (post hoc): one that included studies using a recruitment manoeuvre with subsequent high levels of PEEP, and another that comprised studies using a recruitment manoeuvre, along with a subsequent trial involving a decrement in PEEP settings
In this review, we have found, with moderate‐level evidence, that high levels of PEEP as compared with low levels did not reduce mortality before hospital discharge. Oxygenation, with low‐level evidence, was improved in the high‐PEEP group. The data also show, with low‐level evidence, that high levels of PEEP produced no significant differences in risk of barotrauma and in the number of ventilator‐free days
20 May 2020 New search has been performed This is an updated version of the review first published in 2013
For this review, there are 4 new included studies: Cavalcanti 2017; Hodgson 2011; Hodgson 2019; Kacmarek 2016; 7 new excluded studies: Beitler 2019; Bergez 2019; Chimot 2017; Constantin 2019; Khan 2018; Kung 2019; Pintado 2013; 1 study excluded from the previous review: Huh 2009; and 2 ongoing studies: Antonelli 2019; Goligher 2018
For this updated review, 3 authors have left the work team: Juan Rojas, Rolando Nervi, and Roberto Heredia, and 2 new members have joined: Fernando Villarejo and Celica Irrazabal