Date | Event | Description |
---|---|---|
2 December 2019 | New search has been performed | We added 4 new studies (1 idiopathic cramp trial, 1 liver‐cirrhosis‐associated cramp trial, and 2 pregnancy‐associated cramp trials). We also made a correction to the data entered into the meta‐analysis of cramp intensity and number of cramps per week at 4 weeks for 1 study (specifically, for Frusso 1999, our calculation of MD and SED for these outcomes in the original review was in error). The description of how cramp intensity was analysed in the Methods section was altered to be more explicit, but no changes were made to how data were analysed other than the conversion of risk differences (used in the original review for dichotomous outcomes) to risk ratios. We made this change recognizing risk ratios to be more generalizable. |
2 December 2019 | New citation required and conclusions have changed | We upgraded the certainty of evidence for two outcomes as a result of more data. The review includes new inconclusive data on cramps in people with liver cirrhosis. Christina S Korowny, Michael R Kolber and Nicolas Dugré joined the review team, Karim M Khan withdrew. |