1. Carcinoma of the ovary: FIGO* nomenclature.
Stage | Extent of tumour | Substage | Details |
I | Limited to ovaries | Ia | Limited to 1 ovary, no tumour on surface or capsule rupture, no positive ascites |
Ib | Limited to both ovaries, no tumour on surface or capsule rupture, no positive ascites | ||
Ic | Stage Ia or Ib but with capsule ruptured, tumour on ovarian surface or positive peritoneal washings/ascites | ||
II | Limited to 1 or both ovaries with pelvic extension | IIa | Extension, metastases to uterus, tubes, or a combination |
IIb | Extension to other pelvis tissues | ||
II c | Stage IIa or IIb with tumour on the surface of 1 or both ovaries, or with capsule ruptured, or with positive peritoneal washings/ascites | ||
III | Limited to abdomen with histologically confirmed peritoneal implants outside the pelvis or positive nodes, or both, or extension to small bowel or omentum | IIIa | Tumour grossly limited to the true pelvis with negative regional lymph nodes, microscopic seeding of abdominal peritoneal surfaces or extension to small bowel or mesentery |
IIIb | Macroscopic metastases < 2 cm; negative regional lymph nodes | ||
IIIc | Macroscopic metastases > 2 cm or positive regional lymph nodes, or both | ||
IV | Distant metastases | Growth outside the abdominal cavity (e.g. lung, liver parenchyma (superficial liver metastases is stage III)) |
FIGO: Federation of International Gynaecologists and Obstetricians. * From FIGO 2009 as all included studies used 2009 classification not 2018.