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. 2020 Aug 27;2020(8):CD008213. doi: 10.1002/14651858.CD008213.pub3

Comparison 4. Trabeculotomy‐trabeculectomy plus mitomycin C with regular suture versus trabeculotomy‐trabeculectomy plus mitomycin C with releaseable suture.

Outcome or subgroup title No. of studies No. of participants Statistical method Effect size
4.1 Mean IOP after surgery 1   Mean Difference (IV, Fixed, 95% CI) Subtotals only
4.1.1 6 months or any time point < 1 year (specify) 1 26 Mean Difference (IV, Fixed, 95% CI) 1.20 [‐1.49, 3.89]
4.1.2 1 year 1 26 Mean Difference (IV, Fixed, 95% CI) ‐0.30 [‐3.73, 3.13]
4.1.3 > 1 year (2 years) 1 26 Mean Difference (IV, Fixed, 95% CI) 0.90 [‐1.64, 3.44]
4.2 Proportion with postoperative IOP ≤ 21 mmHg (surgical success) with or without glaucoma medications 1   Risk Ratio (M‐H, Fixed, 95% CI) Subtotals only
4.2.1 6 months or any time point < 1 year (specify) 1 39 Risk Ratio (M‐H, Fixed, 95% CI) 0.95 [0.61, 1.48]
4.2.2 1 year after surgery 1 39 Risk Ratio (M‐H, Fixed, 95% CI) 0.95 [0.61, 1.48]
4.2.3 > 1 year (specify) 1 39 Risk Ratio (M‐H, Fixed, 95% CI) 0.95 [0.61, 1.48]
4.3 Mean corneal diameter 1   Mean Difference (IV, Fixed, 95% CI) Subtotals only
4.3.1 6 months or any time point < 1 year (specify) 1 26 Mean Difference (IV, Fixed, 95% CI) ‐0.60 [‐0.89, ‐0.31]
4.3.2 1 year after surgery 1 26 Mean Difference (IV, Fixed, 95% CI) ‐0.40 [‐0.90, 0.10]
4.3.3 > 1 year (specify) 1 26 Mean Difference (IV, Fixed, 95% CI) ‐0.10 [‐0.68, 0.48]
4.4 Mean axial length 1   Mean Difference (IV, Fixed, 95% CI) Subtotals only
4.4.1 6 months or any time point < 1 year (specify) 1 26 Mean Difference (IV, Fixed, 95% CI) ‐0.86 [‐2.46, 0.74]
4.4.2 1 year after surgery 1 26 Mean Difference (IV, Fixed, 95% CI) ‐1.27 [‐2.17, ‐0.37]
4.4.3 > 1 year (specify) 1 26 Mean Difference (IV, Fixed, 95% CI) 0.11 [‐0.83, 1.05]
4.5 Proportion of children needing repeat surgery, defined as any glaucoma surgery required in the study eye to achieve surgical success excluding corneal (e.g. penetrating keratoplasty), cataract, or retinal surgeries 1   Risk Ratio (M‐H, Fixed, 95% CI) Subtotals only
4.5.1 6 months or any time point < 1 year (specify) 1 39 Risk Ratio (M‐H, Fixed, 95% CI) 1.11 [0.45, 2.70]
4.6 Mean cup/disc ratio 1   Mean Difference (IV, Fixed, 95% CI) Subtotals only
4.6.1 6 months or any time point < 1 year (specify) 1 26 Mean Difference (IV, Fixed, 95% CI) 0.00 [‐0.20, 0.20]
4.6.2 1 year after surgery 1 26 Mean Difference (IV, Fixed, 95% CI) ‐0.20 [‐0.32, ‐0.08]
4.6.3 > 1 year (specify) 1 26 Mean Difference (IV, Fixed, 95% CI) 0.10 [‐0.07, 0.27]