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. 2021 Apr 19;2021(4):CD012654. doi: 10.1002/14651858.CD012654.pub2

IRCT2016111819554N11.

Methods Parallel randomized double‐blinded trial
Participants Men aged 30 to 80 years; sexual dysfunction for at least the six months prior to recruitment; no relationship problems with partner for at least the six months prior to recruitment; Hemoglobin A1c less than 10 & fasting blood sugar less than 200 for at least the six months prior to recruitment; normal serum testosterone and prolactin levels; non‐interference between study drugs with other prescription medications; no history of priapism.
Interventions
  • Ginseng capsule for 10 weeks

  • Bupropion tablet (150 mg) for 10 weeks

  • Sildenafil tablet (50 mg) for 10 weeks

  • Placebo for 10 weeks

Outcomes
  • Erectile dysfunctions

  • Hemoglobin A1c

  • Serum cholesterol level

  • Serum prolactin level

  • Serum testosterone level

  • Serum triglyceride level

  • Serum fasting blood sugar level. Timepoint: first day. Method of measurement: laboratory kits (calorimetry enzymatic).

Notes Available from: www.irct.ir/trial/17480