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. 2021 Feb 9;2021(2):CD008013. doi: 10.1002/14651858.CD008013.pub3

Comparison 1. antidepressant versus placebo.

Outcome or subgroup title No. of studies No. of participants Statistical method Effect size
1.1 Global improvement 2 205 Risk Ratio (M‐H, Random, 95% CI) 1.17 [0.87, 1.56]
1.2 Withdrawals due to adverse events 3 238 Risk Ratio (M‐H, Random, 95% CI) 3.17 [0.65, 15.33]