Bohmer 1988.

Study characteristics
Methods	Study design: double‐blind, randomised Country: Germany Setting: single centre Intention‐to‐treat: not mentioned
Participants	Number of participants randomly assigned: 27 (14 Ginkgo biloba extract, 13 pentoxifylline) Number of participants analysed: 26 Exclusions postrandomisation: 0 Losses to follow‐up: 1 Age (mean): 60.3 (SD 7.3) years (range 44–72 years) Sex: 24 males, 3 females Inclusion criteria: outpatient; high‐grade stenosis for SFA; 1‐side claudication; PFWD 50–200 m; < 30% variance in walking distance during 3‐week placebo induction phase Exclusion criteria: not mentioned
Interventions	Treatment: pentoxifylline, 1200 mg daily Control: Ginkgo biloba extract, 160 mg daily Duration: 24 weeks
Outcomes	Primary: mean PFWD, TWD Secondary: ABI
Notes	Treadmill protocol: 3 km/h at 5% inclination Mean PFWD and TWD expressed in metres only
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Unclear risk	Quote: "randomised." Comment: no other information provided.
Allocation concealment (selection bias)	Unclear risk	Not mentioned.
Blinding of participants and personnel (performance bias) All outcomes	Unclear risk	Quote: "double blind." Comment: no other information available.
Blinding of outcome assessment (detection bias) All outcomes	Unclear risk	Not mentioned.
Incomplete outcome data (attrition bias) All outcomes	Low risk	No incomplete outcome data.
Selective reporting (reporting bias)	Unclear risk	Protocol not available; insufficient information available to permit judgement.
Other bias	Low risk	Study appeared free of other bias.