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Frequency of LOH of PTPRJ and NF2 in human meningiomas of different WHO grade. Established genetic markers were used to explore possible LOH at the PTPRJ and NF2 locus for 32 meningioma cases.
| Tumor type | Number of tumors | |||||
|---|---|---|---|---|---|---|
| PTPRJ informative | LOH (%) | NF2 informative | LOH (%) | PTPRJ + NF2 informative | LOH (%) | |
| All grades | 26 | 10 (38.5) | 26 | 13 (50) | 26 | 9 (34.5) |
| Grade I | 20 | 7 (35) | 20 | 9 (45) | 20 | 6 (30) |
| Grade II/III | 6 | 3 (50) | 6 | 4 (67) | 6 | 3 (50) |
