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. 2011 Mar 16;21(5):558–563. doi: 10.1111/j.1750-3639.2011.00478.x

Figure 2.

Figure 2

Histopathology and evaluation of claudin‐6 immunohistochemistry in a case of atypical teratoid rhabdoid tumor (AT/RT) showing retained SMARCB1 staining. A typical case of AT/RT, composed of large cells, with vescicular nuclei, evident nucleoli and abundant cytoplasm. Neoplastic cells show retained nuclear SMARCB1 staining, even if they show the classic multipotential differentiation, with positivity for smooth muscular actin, cytokeratin and EMA. In a focal area, the tumor also stain for claudin‐6, original magnification 200×.