Study	Reason for exclusion
Forman 2013	Inappropriate study design: SET in the PGS group vs DET in the control group
Forman 2014	Inappropriate study design: SET in the PGS group vs DET in the control group
Gianaroli 1997	Allocation to intervention or control group based on volunteer decision.
Gianaroli 1999	Allocation to intervention or control group based on volunteer decision.
Mersereau 2008	Unknown status: ongoing or stopped. Outcome measures reported as percentages without mentioning the unit of analysis, not possible to calculate the exact numbers.
Moayeri 2016	No data beyond biochemical pregnancy
NCT02265614	Study stopped earlier due to poor recruitment, no published data.
Ozgur 2019	Inappropriate study design: only 1 blastocyst underwent PGT‐A; the rest were morphologically scored
Rubio 2017	Incorrect unit of analysis, e.g. per started cycle. Multiple ovum pick‐ups were allowed to collect multiple oocytes before a transfer was attempted, and it was not possible to calculate the exact numbers per first treatment cycle.
Scott 2013	Only inclusion of patients with an embryo transfer. Study in favour of PGT‐A. If randomisation occurred at cycle start, a percentage would not have had euploid embryos to biopsy or transfer, thus likely altering success rates, based on an intention‐to‐treat analysis.
Stevens 2004	The participants included in this study were also included in another, larger study.
Yang 2012	Only inclusion of patients with an embryo transfer. Study in favour of PGT‐A. If randomisation occurred at cycle start, some percentage would not have had euploid embryos to biopsy or transfer, thus likely altering success rates, based on an intention‐to‐treat analysis.

DET: Double embryo transfer

PGS: Preimplantation genetic screening

PGT‐A: Preimplantation genetic testing for aneuploidies

SET: Single embryo transfer