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. 2020 Oct 24;2020(10):CD013256. doi: 10.1002/14651858.CD013256.pub2

Comparison 1. Corticosteroids versus control.

Outcome or subgroup title No. of studies No. of participants Statistical method Effect size
1.1 Postoperative infection within 30 days of surgery 41   Odds Ratio (IV, Random, 95% CI) Subtotals only
1.1.1 Adjusted Analysis 17   Odds Ratio (IV, Random, 95% CI) 1.70 [1.38, 2.09]
1.1.2 Unadjusted Analysis 24   Odds Ratio (IV, Random, 95% CI) 1.22 [1.03, 1.45]
1.2 Postoperative infection within 30 days of surgery: subgroup UC vs CD 33   Odds Ratio (IV, Random, 95% CI) 1.36 [1.18, 1.57]
1.2.1 Ulcerative colitis 11   Odds Ratio (IV, Random, 95% CI) 1.49 [1.10, 2.02]
1.2.2 Crohn's disease 23   Odds Ratio (IV, Random, 95% CI) 1.32 [1.11, 1.57]
1.3 Postoperative infection within 30 days of surgery: subgroup pre 1998 versus 1998 or after 15   Odds Ratio (IV, Random, 95% CI) 1.72 [1.37, 2.16]
1.3.1 Pre 1998 2   Odds Ratio (IV, Random, 95% CI) 4.22 [1.67, 10.64]
1.3.2 1998 or after 13   Odds Ratio (IV, Random, 95% CI) 1.62 [1.30, 2.01]
1.4 Incisional infections and wound dehiscence 7   Odds Ratio (IV, Random, 95% CI) 1.41 [0.72, 2.74]
1.5 Intra‐abdominal infectious complications 28   Odds Ratio (IV, Random, 95% CI) 1.53 [1.28, 1.84]
1.6 Extra‐abdominal infections 4   Odds Ratio (IV, Random, 95% CI) 1.23 [0.97, 1.55]
1.7 Postoperative infection within 30 days of surgery: sensitivity excluding very high risk of bias 15   Odds Ratio (IV, Random, 95% CI) 1.43 [1.13, 1.81]
1.8 Postoperative infection within 30 days of surgery: sensitivity exclude abstract 36   Odds Ratio (IV, Random, 95% CI) 1.48 [1.28, 1.72]
1.9 Postoperative infection within 30 days of surgery: sensitivity excluding surgery for abscess 21   Odds Ratio (IV, Random, 95% CI) 1.37 [1.14, 1.65]
1.9.1 Adjusted Analysis 9   Odds Ratio (IV, Random, 95% CI) 1.79 [1.35, 2.38]
1.9.2 Unadjusted Analysis 12   Odds Ratio (IV, Random, 95% CI) 1.07 [0.81, 1.40]