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. 2020 Oct 24;2020(10):CD013256. doi: 10.1002/14651858.CD013256.pub2

Comparison 5. Anti‐integrin agents versus control.

Outcome or subgroup title No. of studies No. of participants Statistical method Effect size
5.1 Postoperative infection within 30 days of surgery 9 5157 Odds Ratio (IV, Random, 95% CI) 1.11 [0.76, 1.62]
5.1.1 Adjusted Analysis 2 1022 Odds Ratio (IV, Random, 95% CI) 1.04 [0.79, 1.36]
5.1.2 Unadjusted Analysis 7 4135 Odds Ratio (IV, Random, 95% CI) 1.06 [0.54, 2.10]
5.2 Postoperative infection within 30 days of surgery: subgroup UC vs CD 5   Odds Ratio (IV, Random, 95% CI) 1.04 [0.52, 2.07]
5.2.1 Ulcerative colitis 2   Odds Ratio (IV, Random, 95% CI) 0.61 [0.28, 1.36]
5.2.2 Crohn's disease 4   Odds Ratio (IV, Random, 95% CI) 1.32 [0.51, 3.42]
5.3 Incisional infections and wound dehiscence 6   Odds Ratio (IV, Random, 95% CI) 1.64 [0.77, 3.50]
5.4 Intra‐abdominal infectious complications 5   Odds Ratio (IV, Random, 95% CI) 0.40 [0.14, 1.20]
5.5 Extra‐abdominal infections 5   Odds Ratio (IV, Random, 95% CI) 1.15 [0.43, 3.08]
5.6 Postoperative infection within 30 days of surgery: sensitivity excluding very high risk of bias 3   Odds Ratio (IV, Random, 95% CI) 1.10 [0.79, 1.52]
5.7 Postoperative infection within 30 days of surgery: sensitivity exclude abstract 5   Odds Ratio (IV, Random, 95% CI) 1.06 [0.58, 1.96]
5.8 Postoperative infection within 30 days of surgery: sensitivity excluding surgery for abscess 9   Odds Ratio (IV, Random, 95% CI) 1.11 [0.76, 1.62]
5.8.1 Adjusted Analysis 2   Odds Ratio (IV, Random, 95% CI) 1.04 [0.79, 1.36]
5.8.2 Unadjusted Analysis 7   Odds Ratio (IV, Random, 95% CI) 1.06 [0.54, 2.10]
5.9 Postoperative infection within 30 days of surgery: sensitivity excluding sum of infection studies 7   Odds Ratio (IV, Random, 95% CI) 0.97 [0.73, 1.29]
5.9.1 Adjusted Analysis 2   Odds Ratio (IV, Random, 95% CI) 1.04 [0.79, 1.36]
5.9.2 Unadjusted Analysis 5   Odds Ratio (IV, Random, 95% CI) 0.78 [0.42, 1.47]