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. 2020 Oct 24;2020(10):CD013256. doi: 10.1002/14651858.CD013256.pub2

Alves 2007.

Study characteristics
Methods Retrospective cohort. Study period: 1984 to 2004.
Participants Country: France. CD patients who underwent their first ileocecal resection with primary anastomosis. Patients with temporary stomas were excluded.
Interventions 1. Preoperative steroids (n= 59)
2. No preoperative steroids (n=102)
Outcomes Anastomotic leak and intra‐abdominal abscess within 30 days of surgery
Notes NOS low risk of bias overall
Adjusted OR for st eroids was obtained from stepwise multivariate analysis model.
Risk of bias
Bias Authors' judgement Support for judgement
Representativeness of the exposed cohort Low risk CD database of patients who underwent surgery from 1984 to 2004
Selection of the non exposed cohort Low risk Both groups obtained from the same hospital and time period
Ascertainment of exposure Low risk CD database
Demonstration that outcome of interest was not present at start of study High risk Some patients were found to have Intra‐abdominal abscesses during surgery
Comparability of cohorts (Controlled for critical factor/other medications) High risk Did not report controlling for other medications
Comparability of cohorts (Controlled for additional factor) Low risk Controlled for poor nutritional status
Assessment of outcome Low risk CD database
Was follow‐up long enough for outcomes to occur Low risk 30 days
Adequacy of follow up of cohorts Unclear risk NOS low risk of bias overall