Alves 2007.
Study characteristics | ||
Methods | Retrospective cohort. Study period: 1984 to 2004. | |
Participants | Country: France. CD patients who underwent their first ileocecal resection with primary anastomosis. Patients with temporary stomas were excluded. | |
Interventions | 1. Preoperative steroids (n= 59) 2. No preoperative steroids (n=102) |
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Outcomes | Anastomotic leak and intra‐abdominal abscess within 30 days of surgery | |
Notes | NOS low risk of bias overall Adjusted OR for st eroids was obtained from stepwise multivariate analysis model. |
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Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Representativeness of the exposed cohort | Low risk | CD database of patients who underwent surgery from 1984 to 2004 |
Selection of the non exposed cohort | Low risk | Both groups obtained from the same hospital and time period |
Ascertainment of exposure | Low risk | CD database |
Demonstration that outcome of interest was not present at start of study | High risk | Some patients were found to have Intra‐abdominal abscesses during surgery |
Comparability of cohorts (Controlled for critical factor/other medications) | High risk | Did not report controlling for other medications |
Comparability of cohorts (Controlled for additional factor) | Low risk | Controlled for poor nutritional status |
Assessment of outcome | Low risk | CD database |
Was follow‐up long enough for outcomes to occur | Low risk | 30 days |
Adequacy of follow up of cohorts | Unclear risk | NOS low risk of bias overall |