Coquet‐Reinier 2010.

Study characteristics
Methods	Matched retrospective cohort study. Study period: 1998 to 2008
Participants	Country: France. UC patients who underwent laproscopic restorative proctocolectomy with ileal pouch anal anastomosis
Interventions	1. Preoperative infliximab (n=13) 2. No preoperative infliximab (n=13)
Outcomes	Pelvic abscess and anastomotic leak within 30 days of surgery
Notes	NOS low risk of bias overall
Risk of bias
Bias	Authors' judgement	Support for judgement
Representativeness of the exposed cohort	Low risk	UC patients who underwent laparoscopic IPAA since 1999
Selection of the non exposed cohort	Low risk	Both groups obtained from the same hospital and time period
Ascertainment of exposure	Low risk	Medical records were examined
Demonstration that outcome of interest was not present at start of study	Unclear risk	Information not provided
Comparability of cohorts (Controlled for critical factor/other medications)	High risk	Did not control for other medications
Comparability of cohorts (Controlled for additional factor)	Low risk	Matched for gender, age and procedure type (2 or 3 stage)
Assessment of outcome	Low risk	Medical records were examined
Was follow‐up long enough for outcomes to occur	Low risk	30 days
Adequacy of follow up of cohorts	Unclear risk	Information not provided