Serradori 2013.
Study characteristics | ||
Methods | Retrospective, multicenter (3 institutions) cohort. Study period: 2000 to 2010 | |
Participants | Country: France. CD patients who underwent ileocecal or ileocolonic resection. Patients with temporary stomas were excluded. | |
Interventions | 1. Preoperative anti‐TNF within 8 weeks of surgery 2. Preoperative steroids |
|
Outcomes | Intraabdominal abscess, anastomotic leak, fistula within 30 days of surgery | |
Notes | NOS low risk of bias overall Adjusted ORs for preoperative anti‐TNF and corticosteroids were obtained from multivariate regression analysis. |
|
Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Representativeness of the exposed cohort | Low risk | CD patients who underwent ileocecal or ileocolonic resection from 2000 to 2010 |
Selection of the non exposed cohort | Low risk | Both groups obtained from the same database and time period |
Ascertainment of exposure | Low risk | Medical charts reviewed |
Demonstration that outcome of interest was not present at start of study | High risk | 30 patients had an abscess at the time of surgery |
Comparability of cohorts (Controlled for critical factor/other medications) | Low risk | Controlled for steroids and anti‐TNF use |
Comparability of cohorts (Controlled for additional factor) | Low risk | Also controlled for age, Montreal classification |
Assessment of outcome | Low risk | Medical charts reviewed |
Was follow‐up long enough for outcomes to occur | Low risk | 30 days |
Adequacy of follow up of cohorts | Unclear risk | Information not provided |