Table 2:
Dorsoventral differentially expressed (DE) genes manually curated by function based on GO terms and gene descriptions from UniProt (Anon, 2008).
| FUNCTION | Stage 24 DE Genes | Stage 25 DE Genes | Stage 27 DE Genes |
|---|---|---|---|
| Extracellular Matrix Cell Adhesion |
st3gal5 | col6a3, dcn, pcdhgc5 | postn, itgb5, tnc, mmp11, matn4, itga3, ddr2, col3a1, adam19, rgcc, pkp3, loxla, cdh31, epcam, mcam, pkp1, megf10, nectin1, sorbs3 |
| Angiogenesis | N/A | dcn, map3k3 | thbs2a, loxla, gata6, mcam, ptgis, plcg1, prox1, rgcc, notch3 |
| Cell polarity Actin |
N/A | actr2, was, fnbp1l, fryl, arhgef25 | limch1, prex1, rab11fip2, actc1a, cotl1, ttn, acta2, tpm3, ripor1 |
| Cell migration Cancer |
insr, brd9 | dcn, map3k3 | hgfb, limch1, itgb5, loxla, spata13, epcam, igfbp5, itga3, plcg1, ddr2, megf10, ripor1, prox1, rgcc, arid2, tbx5, tead3, kiaa1549, vwce |
| Growth factors Patterning |
arl6 | tead3, esrp2, foxa2, tbx5, rab7 | hgfb, igfbp5, gata6, mid1, fzd7a, plcg1, fibl3, c3, igf2, pitx3, rgcc, olfml, irx2 |
| Membrane Trafficking Membrane Organization | arl6 | fnbp1l, tmem111, actr2, stx16, rab7, aftph | pkp3, krt18, itga3, tlcd1, gpd1l, mrap, sfxn2, abcc8 |