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. 2021 Mar 18;2021(3):CD011424. doi: 10.1002/14651858.CD011424.pub3

CTRI/2018/05/013970.

Study name Public title: Injury to the lining of the womb to improve chance of pregnancy in couples having sexual intercourse or placement of sperm into the womb
Scientific title: Pipelle curetting as a method of endometrial scratching to increase the clinical pregnancy rate
Methods Randomised controlled trial
Participants Inclusion criteria:
  • Female 18 to 40 years of age

  • Couple having regular unprotected sexual intercourse and unable to conceive for ≥ 12 months

  • Primary or secondary infertility

  • Women with male partner infertility for whom intrauterine insemination (IUI) is planned


Exclusion criteria:
  • Women requiring endometrial biopsy for any other reason (tuberculosis, abnormal uterine bleeding)

Interventions Intervention group: endometrial injury with a pipelle up to Day 12 of the cycle preceding treatment (IUI or intercourse)
Control group: no endometrial injury
Outcomes Clinical pregnancy rate
Starting date June 2018
Contact information S. Tahmina; dr.tahmina.s@gmail.com; +918870730885
Notes CTRI/2018/05/013970
Author correspondence was undertaken to check whether the trial was still ongoing, but we did not receive a response