PACTR201604001405465.

Study name	Public title: Role of endometrial scratch in unexplained infertility (RESCUE): a randomized clinical trial Scientific title: Randomized controlled trial of endometrial Injury in unexplained infertility
Methods	Randomised controlled trial
Participants	Inclusion criteria: Female 18 to 35 years of age Duration of subfertility < 3 years Unexplained infertility (confirmed with semen analysis, basic hormonal profile, pelvic ultrasound and diagnostic laparoscopy, and dye test) No history of previous assisted reproductive technology (ART) Exclusion criteria: Infertility due to male, tubal, anovulatory factors Presence of endometrial pathology as polyp or submucous fibroids Abnormal genital tract bleeding Any of the inclusion criteria is not fulfilled
Interventions	Intervention group: endometrial scratch during diagnostic laparoscopy for infertility with a sharp curette and once again at 3 months' follow‐up with a pipelle in the outpatient clinic Control group: sham endometrial scratch "with use of pipelle of endocervical canal", also twice
Outcomes	Cumulative pregnancy rate, time to pregnancy, clinical pregnancy, miscarriage rate, complications
Starting date	March 2016
Contact information	Mohammed Khairy; mkhairymaklad1973@yahoo.co.uk; 0020862366446
Notes	PACTR201604001405465 Trial completed; submission of manuscript expected soon (confirmed by author correspondence in June 2020)

AMH: anti‐Müllerian hormone; ART: assisted reproductive technology; BMI: body mass index; CAT: Chlamydia antibody titre; FSH: follicle‐stimulating hormone; hMG: human menopausal gonadotropin; HSG: hysterosalpingogram or hysterosalpingography; IUI: intrauterine insemination; IVF: in vitro fertilisation; LH: luteinising hormone; OI: ovulation induction; OS: ovarian stimulation; TB: tuberculosis; TSH: thyroid‐stimulating hormone; VAS: visual analogue scale; WHO: World Health Organization.