2. Ongoing trials for prevention: actively recruiting or completed; not yet published.
Trial registration number; trial registry | Location(s) | Interventions; population; abbreviated name | Recruitment status | Estimated completion | Target enrolment |
NCT04333732 ClinicalTrials.gov |
USA | Low‐/medium‐/high‐dose chloroquine vs placebo Healthcare workers |
Recruiting | February 2021 | 55,000 |
NCT04303507 ClinicalTrials.gov |
Europe, Asia, Africa | HQC vs CQ vs placebo Healthcare workers COPCOV |
Recruiting | April 2021 | 40,000 |
NCT04334928 ClinicalTrials.gov | Spain | Emtricitabine/tenofovir (Truvada) vs HCQ vs Truvada + HCQ vs placebo Healthcare workers EPICOS |
Recruiting | June 2020 | 4000 |
NCT04334148 ClinicalTrials.gov |
USA | HCQ vs placebo Healthcare workers |
Recruiting | July 2020 | 15,000 |
NCT04363450 ClinicalTrials.gov |
USA | HCQ vs placebo Healthcare workers (pre‐exposure) HCQPreP |
Recruiting | July 2020 | 1700 |
NCT04318444 ClinicalTrials.gov |
USA | HCQ vs placebo Household contacts (postexposure) |
Recruiting | March 2021 | 1600 |
NCT04341441 ClinicalTrials.gov |
USA | Daily HCQ vs weekly HCQ vs placebo Healthcare workers and first responders |
Recruiting | June 2020 | 3000 |
IRCT20190122042450N4 Iranian Clinical Trials Registry | Iran | HCQ vs no HCQ All contacts (postexposure) |
Completed | Not reported | 1000 |
ISRCTN14326006 ISRCTN registry |
Canada | HCQ vs placebo Healthcare workers |
Recruiting | January 2022 | 988 |
NCT04363827 ClinicalTrials.gov |
Italy | HCQ vs no HCQ All contacts |
Recruiting | September 2020 | 2300 |
NCT04352933 ClinicalTrials.gov |
UK | HCQ weekly vs HCQ daily vs placebo Healthcare workers |
Recruiting | October 2020 | 1000 |
NCT04353037 ClinicalTrials.gov |
USA | HCQ vs placebo Healthcare workers |
Recruiting | April 2021 | 850 |
ACTRN12620000501943 ANZCTR |
Australia | HCQ vs placebo Healthcare workers |
Recruiting | December 2020 | 2250 |
NCT04374942 ClinicalTrials.gov |
USA | HCQ vs placebo Healthcare workers |
Recruiting | January 2022 | 988 |
EudraCT 2020‐001987‐28 EudraCT |
Italy | HCQ vs no HCQ Healthcare workers |
Recruiting | Not reported | 1000 |
CQ, chloroquine; HCQ, hydroxychloroquine