Comparison 1. NSAID versus placebo.

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1.1 Adequate pain relief as reported by the woman.	11	946	Risk Ratio (M‐H, Fixed, 95% CI)	1.66 [1.45, 1.91]
1.1.1 Aspirin 650 mg	6	282	Risk Ratio (M‐H, Fixed, 95% CI)	1.33 [1.09, 1.61]
1.1.2 Naproxen 275 mg	1	45	Risk Ratio (M‐H, Fixed, 95% CI)	1.50 [0.98, 2.31]
1.1.3 Naproxen 300 mg	1	52	Risk Ratio (M‐H, Fixed, 95% CI)	1.46 [0.90, 2.36]
1.1.4 Naproxen 550 mg	1	60	Risk Ratio (M‐H, Fixed, 95% CI)	2.56 [1.43, 4.57]
1.1.5 Naproxen 600 mg	1	53	Risk Ratio (M‐H, Fixed, 95% CI)	1.54 [1.00, 2.38]
1.1.6 Flurbiprofen 50 mg	1	46	Risk Ratio (M‐H, Fixed, 95% CI)	1.39 [0.93, 2.08]
1.1.7 Ketorolac 5 mg	1	40	Risk Ratio (M‐H, Fixed, 95% CI)	1.73 [0.92, 3.27]
1.1.8 Ketorolac 10 mg	1	40	Risk Ratio (M‐H, Fixed, 95% CI)	1.67 [0.88, 3.16]
1.1.9 Fenoprofen 12.5 mg	1	32	Risk Ratio (M‐H, Fixed, 95% CI)	2.22 [0.37, 13.48]
1.1.10 Fenoprofen 25 mg	1	32	Risk Ratio (M‐H, Fixed, 95% CI)	2.78 [0.47, 16.56]
1.1.11 Fenoprofen 50 mg	2	66	Risk Ratio (M‐H, Fixed, 95% CI)	3.72 [1.03, 13.39]
1.1.12 Fenoprofen 100 mg	2	69	Risk Ratio (M‐H, Fixed, 95% CI)	2.86 [1.04, 7.89]
1.1.13 Fenoprofen 200 mg	3	93	Risk Ratio (M‐H, Fixed, 95% CI)	2.67 [1.15, 6.23]
1.1.14 Fenoprofen 300 mg	1	36	Risk Ratio (M‐H, Fixed, 95% CI)	2.41 [0.73, 7.99]
1.2 Need for additional pain relief	4	375	Risk Ratio (M‐H, Fixed, 95% CI)	0.15 [0.07, 0.33]
1.2.1 Aspirin 650 mg	2	85	Risk Ratio (M‐H, Fixed, 95% CI)	0.11 [0.02, 0.63]
1.2.2 Ketorolac 5 mg	1	40	Risk Ratio (M‐H, Fixed, 95% CI)	0.17 [0.02, 1.65]
1.2.3 Ketorolac 10 mg	1	40	Risk Ratio (M‐H, Fixed, 95% CI)	0.17 [0.02, 1.65]
1.2.4 Naproxen 275 mg	1	45	Risk Ratio (M‐H, Fixed, 95% CI)	0.10 [0.01, 2.02]
1.2.5 Naproxen 300 mg	1	52	Risk Ratio (M‐H, Fixed, 95% CI)	0.10 [0.01, 1.98]
1.2.6 Naproxen 600 mg	1	53	Risk Ratio (M‐H, Fixed, 95% CI)	0.11 [0.01, 2.09]
1.2.7 Naproxen 550 mg	1	60	Risk Ratio (M‐H, Fixed, 95% CI)	0.22 [0.05, 0.94]
1.3 Maternal adverse events	9	598	Risk Ratio (M‐H, Fixed, 95% CI)	1.05 [0.78, 1.41]
1.3.1 Aspirin 650 mg	6	238	Risk Ratio (M‐H, Fixed, 95% CI)	0.93 [0.58, 1.47]
1.3.2 Flurbiprofen 50 mg	1	46	Risk Ratio (M‐H, Fixed, 95% CI)	1.07 [0.31, 3.71]
1.3.3 Naproxen 275 mg	1	45	Risk Ratio (M‐H, Fixed, 95% CI)	1.25 [0.27, 5.70]
1.3.4 Naproxen 300 mg	1	52	Risk Ratio (M‐H, Fixed, 95% CI)	0.87 [0.35, 2.21]
1.3.5 Naproxen 550 mg	1	60	Risk Ratio (M‐H, Fixed, 95% CI)	2.00 [0.67, 5.94]
1.3.6 Naproxen 600 mg	1	53	Risk Ratio (M‐H, Fixed, 95% CI)	0.93 [0.36, 2.36]
1.3.7 Ketorolac 5 mg	1	40	Risk Ratio (M‐H, Fixed, 95% CI)	1.00 [0.24, 4.18]
1.3.8 Ketorolac 10 mg	1	40	Risk Ratio (M‐H, Fixed, 95% CI)	1.17 [0.29, 4.73]
1.3.9 Fenoprofen 200 mg	1	24	Risk Ratio (M‐H, Fixed, 95% CI)	1.20 [0.50, 2.88]