NCT04169984.

Study name	Myofunctional Therapy in Patients With Mild‐moderate Sleep Apnea.
Methods	Parallel, RCT.
Participants	Inclusion criteria: patients over 18 and under 80 years old, with AHI from 5 to 29 assessed by a respiratory polygraphy, and absence of daytime sleepiness (ESS lower than 12). Exclusion criteria: refractory high blood pressure (blood pressure that is not controlled with three antihypertensive drugs, including a diuretic); ictus, transient ischaemic attack, neuromuscular diseases, acute coronary syndrome or hospitalisation for worsening heart failure, in the previous 30 days; professional drivers, profession of risk or respiratory failure; previous surgical intervention for the treatment of sleep apnoea (those patients who have refused treatment with CPAP or mandibular advancement devices after 1 month of not using them, could be included).
Interventions	Intervention: myofunctional therapy. Comparator: sham comparator.
Outcomes	Primary Outcome Measures: Apnea Hypopnea Index. Secondary Outcome Measures: Change in snoring. Change in oximeter parameters. Degree of therapeutic adherence. Quality of life (SF‐36). Sleep quality (PQSI). Daytime sleepiness (ESS).
Starting date	Study Start Date: June 2020. Estimated Study Completion Date: June 2022.
Contact information	Irene M Cano Pumarega. Hospital Universitario Ramón y Cajal, Pneumology Department. Madrid. Spain.
Notes	Information from ClinicalTrials.com.