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. 2021 Feb 9;2021(2):CD013053. doi: 10.1002/14651858.CD013053.pub2

4. Resolution of ear discharge.

Reference Unit of randomisation Reported Definition Otoscopically confirmed? Time points Notes
de Miguel 1999 Person Person "global index of clinical microbiological cure" Yes 1 to 2 weeks (7 days)
Esposito 1990 Person Person "clinically cured" Unclear 1 to 2 weeks (5 to 11 days), 2 to 4 weeks (19 to 24 days) Results examined but not reported at 1 to 2 weeks
Esposito 1992 Person Person "clinically and bacteriologically cured" Unclear 2 to 4 weeks (19 to 31 days) Authors describe follow‐up as taking place 14 to 21 days after treatment cessation (treatment was for 5 to 10 days)
Povedano 1995 Person Person "healed" ("curation") Unclear 1 to 2 weeks (10 days) Results described as healing, improvement or failure
"Healing" should correspond with "dry ear" since even patients with "improvement" were described as no longer having otorrhoea
Ramos 2003 Person Person "cured" according to "indices de curacion" Yes 1 to 2 weeks (10 days)
Yuen 1994 Person Person "dry" Unclear 1 to 2 weeks (end of second week) No information provided on whether there were participants with bilateral CSOM and how these data were counted

CSOM: chronic suppurative otitis media