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. 2021 Feb 10;2021(2):CD012882. doi: 10.1002/14651858.CD012882.pub2

Comparison 1. iCCM versus usual facility services.

Outcome or subgroup title No. of studies No. of participants Statistical method Effect size
1.1 Comparison 1 iCCM vs usual facility services: coverage of appropriate treatment by an appropriate provider (CBA) 2 5898 Risk Ratio (M‐H, Random, 95% CI) 0.96 [0.77, 1.19]
1.1.1 Diarrhoea (CBA) 2 1749 Risk Ratio (M‐H, Random, 95% CI) 2.92 [0.27, 31.60]
1.1.2 Malaria (CBA) 2 4149 Risk Ratio (M‐H, Random, 95% CI) 0.85 [0.68, 1.06]
1.2 Comparison 1 iCCM vs usual facility services: coverage of appropriate treatment by an iCCM provider (CBA) 1 4651 Risk Ratio (M‐H, Random, 95% CI) 124.40 [17.37, 890.83]
1.2.1 Diarrhoea (CBA) 1 1375 Risk Ratio (M‐H, Random, 95% CI) 128.99 [7.99, 2083.46]
1.2.2 Malaria (CBA) 1 3276 Risk Ratio (M‐H, Random, 95% CI) 119.96 [7.40, 1945.55]
1.3 Comparison 1 iCCM vs usual facility services: mortality (cRCT) 2   Risk Ratio (IV, Random, 95% CI) Subtotals only
1.3.1 Neonatal mortality (cluster randomized controlled trial (cRCT)) 2 65209 Risk Ratio (IV, Random, 95% CI) 1.01 [0.77, 1.33]
1.3.2 Infant mortality (cRCT) 2 65209 Risk Ratio (IV, Random, 95% CI) 0.98 [0.72, 1.34]
1.3.3 Under‐five mortality (cRCT) 1 4729 Risk Ratio (IV, Random, 95% CI) 1.16 [0.99, 1.36]
1.4 Comparison 1 iCCM vs usual facility services: coverage of careseeking to an appropriate provider of treatment services (cRCT) 2 9853 Risk Ratio (M‐H, Random, 95% CI) 1.68 [1.24, 2.27]
1.4.1 Diarrhoea (cRCT) 2 3049 Risk Ratio (M‐H, Random, 95% CI) 1.44 [1.12, 1.85]
1.4.2 Fever (cRCT) 1 1101 Risk Ratio (M‐H, Random, 95% CI) 1.61 [1.37, 1.90]
1.4.3 Suspected pneumonia (cRCT) 2 1328 Risk Ratio (M‐H, Random, 95% CI) 1.39 [1.03, 1.88]
1.4.4 Newborn local infection (cRCT) 1 2096 Risk Ratio (M‐H, Random, 95% CI) 4.62 [3.92, 5.44]
1.4.5 Newborn danger signs (cRCT) 1 2279 Risk Ratio (M‐H, Random, 95% CI) 1.59 [1.43, 1.77]
1.5 Comparison 1 iCCM vs usual facility services: coverage of careseeking to an appropriate provider of treatment services (CBA) 3 8406 Risk Ratio (M‐H, Random, 95% CI) 1.30 [1.01, 1.66]
1.5.1 Diarrhoea (CBA) 3 2028 Risk Ratio (M‐H, Random, 95% CI) 1.14 [0.91, 1.41]
1.5.2 Fever (CBA) 3 4509 Risk Ratio (M‐H, Random, 95% CI) 1.57 [0.57, 4.31]
1.5.3 Suspected pneumonia (CBA) 3 1869 Risk Ratio (M‐H, Random, 95% CI) 1.15 [1.06, 1.24]
1.6 Comparison 1 iCCM vs usual facility services: coverage of careseeking to an iCCM provider (CBA) 2 6581 Risk Ratio (M‐H, Random, 95% CI) 158.58 [51.04, 492.70]
1.6.1 Diarrhoea (CBA) 2 1654 Risk Ratio (M‐H, Random, 95% CI) 140.28 [19.66, 1000.95]
1.6.2 Fever (CBA) 2 3657 Risk Ratio (M‐H, Random, 95% CI) 253.13 [35.57, 1801.37]
1.6.3 Suspected pneumonia (CBA) 2 1270 Risk Ratio (M‐H, Random, 95% CI) 112.26 [15.77, 799.31]