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. 2020 Oct 22;2020(10):CD002125. doi: 10.1002/14651858.CD002125.pub4

Comparison 2. Proximal tubal occlusion (all methods) vs laparoscopic salpingectomy.

Outcome or subgroup title No. of studies No. of participants Statistical method Effect size
2.1 Live birth rate 2   Risk Ratio (M‐H, Fixed, 95% CI) Subtotals only
2.1.1 Proximal tubal occlusion (laparoscopy) vs laparoscopic salpingectomy 1 165 Risk Ratio (M‐H, Fixed, 95% CI) 1.21 [0.76, 1.95]
2.1.2 Proximal tubal occlusion (hysteroscopy) vs laparoscopic salpingectomy 1 85 Risk Ratio (M‐H, Fixed, 95% CI) 0.46 [0.24, 0.89]
2.2 Surgical complication rate ‐ wound infection 1 85 Peto Odds Ratio (Peto, Fixed, 95% CI) 0.14 [0.00, 6.98]
2.2.1 Proximal tubal occlusion (hysteroscopy) vs laparoscopic salpingectomy 1 85 Peto Odds Ratio (Peto, Fixed, 95% CI) 0.14 [0.00, 6.98]
2.3 Surgical complication rate ‐ pelvic infection 1   Peto Odds Ratio (Peto, Fixed, 95% CI) Subtotals only
2.3.1 Proximal tubal occlusion (hysteroscopy) vs laparoscopic salpingectomy 1 85 Peto Odds Ratio (Peto, Fixed, 95% CI) 7.57 [0.15, 381.46]
2.4 Clinical pregnancy rate 4   Risk Ratio (M‐H, Fixed, 95% CI) Subtotals only
2.4.1 Proximal tubal occlusion (laparoscopy) vs laparoscopic salpingectomy 3 347 Risk Ratio (M‐H, Fixed, 95% CI) 0.81 [0.62, 1.07]
2.4.2 Proximal tubal occlusion (hysteroscopy) vs laparoscopic salpingectomy 1 85 Risk Ratio (M‐H, Fixed, 95% CI) 0.53 [0.32, 0.89]
2.5 Multiple pregnancy rate 1   Peto Odds Ratio (Peto, Fixed, 95% CI) Subtotals only
2.5.1 Proximal tubal occlusion (hysteroscopy) vs laparoscopic salpingectomy 1 85 Peto Odds Ratio (Peto, Fixed, 95% CI) 0.14 [0.00, 6.98]
2.6 Miscarriage rate 3   Peto Odds Ratio (Peto, Fixed, 95% CI) Subtotals only
2.6.1 Proximal tubal occlusion (laparoscopy) vs laparoscopic salpingectomy 2 265 Peto Odds Ratio (Peto, Fixed, 95% CI) 0.74 [0.16, 3.34]
2.6.2 Proximal tubal occlusion (hysteroscopy) vs laparoscopic salpingectomy 1 85 Peto Odds Ratio (Peto, Fixed, 95% CI) 2.03 [0.21, 20.04]
2.7 Ectopic pregnancy rate 2   Peto Odds Ratio (Peto, Fixed, 95% CI) Subtotals only
2.7.1 Proximal tubal occlusion (laparoscopy) vs laparoscopic salpingectomy 1 100 Peto Odds Ratio (Peto, Fixed, 95% CI) 7.39 [0.15, 372.38]
2.7.2 Proximal tubal occlusion (hysteroscopy) vs laparoscopic salpingectomy 1 85 Peto Odds Ratio (Peto, Fixed, 95% CI) Not estimable
2.8 Mean number of oocytes 2 265 Mean Difference (IV, Fixed, 95% CI) 0.40 [‐0.67, 1.48]
2.8.1 Proximal tubal occlusion (laparoscopy) vs laparoscopic salpingectomy 2 265 Mean Difference (IV, Fixed, 95% CI) 0.40 [‐0.67, 1.48]
2.9 Mean number of embryos 2   Mean Difference (IV, Fixed, 95% CI) Subtotals only
2.9.1 Proximal tubal occlusion (laparoscopy) vs laparoscopic salpingectomy 1 100 Mean Difference (IV, Fixed, 95% CI) 0.17 [‐1.38, 1.72]
2.9.2 Proximal tubal occlusion (hysteroscopy) vs laparoscopic salpingectomy 1 85 Mean Difference (IV, Fixed, 95% CI) 0.10 [‐1.77, 1.97]
2.10 Multiple pregnancy rate (per clinical pregnancy) 1   Peto Odds Ratio (Peto, Fixed, 95% CI) Subtotals only
2.10.1 Proximal tubal occlusion (hysteroscopy) vs laparoscopic salpingectomy 1 38 Peto Odds Ratio (Peto, Fixed, 95% CI) 0.22 [0.00, 13.62]
2.11 Miscarriage rate (per clinical pregnancy) 3   Peto Odds Ratio (Peto, Fixed, 95% CI) Subtotals only
2.11.1 Proximal tubal occlusion (laparoscopy) vs laparoscopic salpingectomy 2 95 Peto Odds Ratio (Peto, Fixed, 95% CI) 0.82 [0.17, 3.86]
2.11.2 Proximal tubal occlusion (hysteroscopy) vs laparoscopic salpingectomy 1 38 Peto Odds Ratio (Peto, Fixed, 95% CI) 4.59 [0.40, 53.35]