Table 3.

Gene expression of inflammatory cytokines in each of the gastro-esophageal reflux disease phenotypes compared with the control group and in the non-erosive subgroup

	IL-1β Mean ± SEM p value	IL-6 Mean ± SEM p value	IL-8 Mean ± SEM p value	IL-10 Mean ± SEM p value	INF-γ Mean ± SEM p value	TNF-α Mean ± SEM p value	MMP3 Mean ± SEM p value	MMP9 Mean ± SEM p value
Barrett’s Esophagus versus Control	0.057 ± 0.050 N.S	0.002 ± 0.005 N.S	0.24 ± 0.01 0.010	0.024 ± 0.025 N.S	0.05 ± 0.04 N.S	0.04 ± 0.03 N.S	0.018 ± 0.033 N.S	0.023 ± 0.04 N.S
Erosive esophagitisversus Control	0.46 ± 0.031 0.003	0.03 ± 0.002 0.020	0.010 ± .007 N.S	0.010 ± 0.009 0.043	0.001 ± 0.003 N.S	0.002 ± 0.001 N.S	0.003 ± 0.002 N.S	0.003 ± 0.002 N.S
Abnormal acid exposure versus Control	0.19 ± 0.10 0.0001	0.057 ± 0.047 0.012	0.023 ± 0.017 N.S	0.01 ± 0.01 N.S	0.018 ± 0.013 0.001	0.049 ± 0.028 0.0001	0.009 ± 0.007 N.S	0.005 ± 0.001 N.S
Abnormal acid exposure versus Normal Acid Exposure	0.16 ± 0.10 0.001	0.04 ± 0.05 N.S	0.011 ± 0.023 N.S	0.001 ± 0.003 N.S	0.004 ± 0.014 N.S	0.03 ± 0.030 0.036	0.03 ± 0.09 N.S	0.006 ± 0.005 N.S

Error of the mean (SEM), No Significative (NS)