Doenicke 2004.

Methods	Randomized controlled trial
Participants	Patients undergoing surgery from different disciplines (general surgery, orthopaedic surgery, and urology)
Interventions	5 mg/kg cimetidine i.v. + 0.1 mg/kg dimetindene i.v. (20 minutes before induction of anaesthesia), 1.25 mg/kg ranitidine i.v. + 0.1 mg/kg dimetindene i.v. (20 minutes before induction of anaesthesia), 300 mg ranitidine p.o. + 0.1 mg/kg dimetindene i.v. (1 to 2 hours before induction of anaesthesia), 20 mL saline solution i.v. (20 minutes before induction of anaesthesia)
Outcomes	Nausea, vomiting
Notes	Study identified in search update; data will be included in next update of the review