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. 2020 Sep 29;2020(9):CD008294. doi: 10.1002/14651858.CD008294.pub5

Comparison 5. Pine bark extract versus control: DM type I.

Outcome or subgroup title No. of studies No. of participants Statistical method Effect size
5.1 Microcirculation‐related symptom scores: oral Pycnogenol® 1   Mean Difference (IV, Fixed, 95% CI) Totals not selected
5.1.1 At six weeks 1   Mean Difference (IV, Fixed, 95% CI) Totals not selected
5.2 Microcirculation‐related symptom scores: local Pycnogenol® 1   Mean Difference (IV, Fixed, 95% CI) Totals not selected
5.2.1 At six weeks 1   Mean Difference (IV, Fixed, 95% CI) Totals not selected
5.3 Microcirculation‐related symptom scores: oral and local Pycnogenol® 1   Mean Difference (IV, Fixed, 95% CI) Totals not selected
5.3.1 At six weeks 1   Mean Difference (IV, Fixed, 95% CI) Totals not selected
5.4 Area of ulceration: oral Pycnogenol® 1   Mean Difference (IV, Fixed, 95% CI) Totals not selected
5.4.1 At six weeks 1   Mean Difference (IV, Fixed, 95% CI) Totals not selected
5.5 Area of ulceration: local Pycnogenol® 1   Mean Difference (IV, Fixed, 95% CI) Totals not selected
5.5.1 At six weeks 1   Mean Difference (IV, Fixed, 95% CI) Totals not selected
5.6 Area of ulceration: oral and local Pycnogenol® (mm²) 1   Mean Difference (IV, Fixed, 95% CI) Totals not selected
5.6.1 At six weeks 1   Mean Difference (IV, Fixed, 95% CI) Totals not selected
5.7 Transcutaneous PO2: oral Pycnogenol® 1   Mean Difference (IV, Fixed, 95% CI) Totals not selected
5.7.1 At six weeks 1   Mean Difference (IV, Fixed, 95% CI) Totals not selected
5.8 Transcutaneous PCO2: oral Pycnogenol® 1   Mean Difference (IV, Fixed, 95% CI) Totals not selected
5.8.1 At six weeks 1   Mean Difference (IV, Fixed, 95% CI) Totals not selected
5.9 Transcutaneous PO2: oral and local Pycnogenol® 1   Mean Difference (IV, Fixed, 95% CI) Totals not selected
5.9.1 At six weeks 1   Mean Difference (IV, Fixed, 95% CI) Totals not selected
5.10 Transcutaneous PCO2: oral and local Pycnogenol® 1   Mean Difference (IV, Fixed, 95% CI) Totals not selected
5.10.1 At six weeks 1   Mean Difference (IV, Fixed, 95% CI) Totals not selected
5.11 Skin flux at rest: oral Pycnogenol® 1   Mean Difference (IV, Fixed, 95% CI) Totals not selected
5.11.1 At six weeks 1   Mean Difference (IV, Fixed, 95% CI) Totals not selected
5.12 Skin flux at rest: oral and local Pycnogenol® 1   Mean Difference (IV, Fixed, 95% CI) Totals not selected
5.12.1 At six weeks 1   Mean Difference (IV, Fixed, 95% CI) Totals not selected