4. Sensitivity analysis for eczema .

Analysis	N trials	Nintervention	N control	Pooled riskratio	95% CI
Primary: Eczema by1 to 2years	7a	1489	1586	1.03	0.81 to 1.31
Sensitivity: Eczema by 1 to 2 years including aggregate data	8b	1518	1617	0.97	0.75 to 1.25
Eczema by 1 to 2 years using UK Working Party Criteria only	6c	1420	1499	1.02	0.78 to 1.34
Eczema by 1 to 2 years including all 4 arms from the PreventADALL trial	7a	1993	2183	1.03	0.81 to 1.31
Eczema by 1 to 2 years, low risk of bias data only	3d	868	871	0.97	0.81 to 1.17
Eczema by 1 to 2 years, excluding non‐prospectively acquired data	6e	1451	1550	1.08	0.84 to 1.37
Eczema by 6 months to 2 years	9f	1549	1688	0.89	0.70 to 1.14

^aChalmers 2020; Dissanayake 2019; Lowe 2018a; McClanahan 2019; Skjerven 2020; NCT03376243; Yonezawa 2018. ^bChalmers 2020; Dissanayake 2019; Lowe 2018a; McClanahan 2019; Migacheva 2018; Skjerven 2020; NCT03376243; Yonezawa 2018. ^cChalmers 2020; Dissanayake 2019; Lowe 2018a; McClanahan 2019; Skjerven 2020; NCT03376243. ^dChalmers 2020; Dissanayake 2019; Lowe 2018a. ^eChalmers 2020; Dissanayake 2019; McClanahan 2019; Skjerven 2020; NCT03376243; Yonezawa 2018. ^fChalmers 2020; Dissanayake 2019; Horimukai 2014; Lowe 2018a; McClanahan 2019; Simpson 2014; Skjerven 2020; NCT03376243; Yonezawa 2018.