Da Cunha 2008.

Study characteristics
Methods	Study design: randomised clinical trial Recruitment date: infants delivered between 13 September 2005 and 14 March 2006  Treatment arms: 2 AD follow‐up: time points: first bath (first collection), 30 minutes after bath (second collection), and 24 hours after bath (third collection)
Participants	Randomised: N = 112 (chlorhexidine, experimental group n = 56, neutral liquid soap control group n = 56) Inclusion criteria: normal term newborns with gestational age 37 and 42 weeks  Exclusion criteria:  Skin breakdown Congenital infection Premature rupture of membranes for over 18 hours Foetid amniotic fluid HIV+ mother Mother with suspicion of or with bacterial infection before delivery or presenting axillary temperature > 37.8C Hospitalisation before the bath at 24 hours  Second bath before 24 hours
Interventions	Intervention: chlorhexidine liquid soap bath, admission bath between 1 and 1.5 hours after birth  Comparator: neutral liquid soap bath, admission bath same as above  Moisturiser/Emollient: neutral liquid soap (ingredients: Texapon SBN (detergent), Dehyton KB (cocamide), Plantaren 2000 (detergent), Glycerin (emollient), Coperlan KDB (thickener), citric acid,  deionized water, pH = 7)  Chlorhexidine liquid soap bath (chlorhexidine digluconate liquid soap at 0.4%, resulting from dilution of 10 mL of chlorhexidine digluconate liquid soap at 4% in 90 mL of warm water that released 0.25% chlorhexidine)
Outcomes	Staphylococcus aureus skin colonisation  Adverse effects: none reported
Identification	Country: Brazil  Setting: Obstetric Centre of Hospital de Clinicas de Porto Alegre Sponsorship source: this study was supported by the Fundo de Incentivo à Pesquisa (Research Incentive Fund) of Hospital de Clínicas de Porto Alegre (FIPE/HCPA), and Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPQ)
Declarations of interest	None reported in publication
Notes