Date	Event	Description
28 March 2020	New citation required and conclusions have changed	7 new RCTs were included in this update and conclusions are more certain
2 March 2020	Amended	Decision to not include total cardiovascular events as a composite outcome as it was not reported consistently in the different trials
18 November 2011	New search has been performed	Minor numerical typographical errors corrected.
12 August 2008	Amended	Converted to new review format.
11 November 2003	Amended	Minor changes included in the protocol