Figure 3.

Knockdown of FABP4 suppresses Th17 differentiation of naive T cells through paracrine mechanisms

Naive T cells were cultured under Treg or Th17 cell-polarizing conditions with or without primary macrophages-CM. (A and B) The percentage of Tregs (A) or Th17 cells (B) was assessed by FACS. Naive T cells were cultured under Treg or Th17 cell-polarizing conditions with or without rhFABP4. (C and D) The percentage of Tregs (C) or Th17 cells (D) was assessed by FACS. Data are expressed as representative images or the mean ± SD of n = 3 experiments. ns, not significant, ∗∗p < 0.01, ∗∗∗p < 0.001.