Comparison 2. Antidepressants vs treatment as usual.

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
2.1 Depression remission (early phase)	1	218	Risk Ratio (M‐H, Random, 95% CI)	2.31 [1.50, 3.54]
2.2 Severity of depression ‐ EPDS (early phase)	1	225	Mean Difference (IV, Random, 95% CI)	‐2.50 [‐3.85, ‐1.15]
2.3 Treatment acceptability ‐ dropouts	1	254	Risk Ratio (M‐H, Random, 95% CI)	1.71 [0.91, 3.23]
2.4 Parenting‐related outcomes ‐ MAMA (early phase)	1	192	Mean Difference (IV, Random, 95% CI)	1.80 [0.18, 3.42]
2.5 Parenting‐related outcomes ‐ MAMA (continuation phase)	1	183	Mean Difference (IV, Random, 95% CI)	1.00 [‐0.45, 2.45]
2.6 Quality of life ‐ SF‐12 mental health	1	175	Mean Difference (IV, Random, 95% CI)	0.45 [0.21, 0.69]
2.7 Quality of life ‐ SF‐12 physical health	1	175	Mean Difference (IV, Random, 95% CI)	0.03 [‐0.25, 0.31]
2.8 Quality of life ‐ EQ5D utility score	1	198	Mean Difference (IV, Random, 95% CI)	0.05 [‐0.01, 0.11]
2.9 Quality of life ‐ EQ5D visual analogue scale	1	204	Mean Difference (IV, Random, 95% CI)	5.10 [‐1.62, 11.82]