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. 2021 Feb 13;2021(2):CD013560. doi: 10.1002/14651858.CD013560.pub2

Comparison 4. Antidepressants vs psychosocial interventions.

Outcome or subgroup title No. of studies No. of participants Statistical method Effect size
4.1 Depression remission (continuation phase) 1 206 Risk Ratio (M‐H, Random, 95% CI) 1.20 [0.95, 1.53]
4.2 Severity of depression ‐ EPDS (continuation phase) 1 206 Mean Difference (IV, Random, 95% CI) ‐1.00 [‐2.54, 0.54]
4.3 Treatment acceptability ‐ dropouts 1 254 Risk Ratio (M‐H, Random, 95% CI) 1.94 [1.12, 3.35]
4.4 Parenting‐related outcomes ‐ MAMA (continuation phase) 1 183 Mean Difference (IV, Random, 95% CI) 1.00 [‐0.45, 2.45]
4.5 Quality of life ‐ SF12 mental health 1 169 Mean Difference (IV, Random, 95% CI) 0.13 [‐0.15, 0.41]
4.6 Quality of life ‐ SF12 physical health 1 169 Mean Difference (IV, Random, 95% CI) 0.19 [‐0.09, 0.47]
4.7 Quality of life ‐ EQ‐5D utility score 1 194 Mean Difference (IV, Random, 95% CI) ‐0.01 [‐0.08, 0.06]
4.8 Quality of life ‐ EQ‐5D visual analogue scale 1 194 Mean Difference (IV, Random, 95% CI) ‐0.80 [‐9.08, 7.48]