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. 2021 Feb 13;2021(2):CD013560. doi: 10.1002/14651858.CD013560.pub2

Comparison 5. Antidepressant vs other pharmacological intervention.

Outcome or subgroup title No. of studies No. of participants Statistical method Effect size
5.1 Depression response ‐ acute phase 2 165 Risk Ratio (M‐H, Fixed, 95% CI) 0.98 [0.76, 1.27]
5.2 Depression remission ‐ acute phase 2 165 Risk Ratio (M‐H, Fixed, 95% CI) 0.98 [0.68, 1.41]
5.3 Depression response ‐ early phase 1 109 Risk Ratio (M‐H, Fixed, 95% CI) 0.82 [0.56, 1.19]
5.4 Depression remission ‐ early phase 1 109 Risk Ratio (M‐H, Fixed, 95% CI) 0.92 [0.51, 1.67]
5.5 Depression severity ‐ HAM‐D (acute phase) 2 165 Mean Difference (IV, Random, 95% CI) ‐0.65 [‐3.18, 1.87]
5.6 Treatment acceptability ‐ dropouts 1 109 Risk Ratio (M‐H, Random, 95% CI) 1.74 [0.99, 3.06]