Comparison 1. Newer generation antidepressants (NGAs).

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1.1 Repetition of SH by post‐intervention (NGA class)	2	129	Odds Ratio (M‐H, Random, 95% CI)	0.59 [0.29, 1.19]
1.1.1 Mianserin vs. Placebo	1	38	Odds Ratio (M‐H, Random, 95% CI)	0.67 [0.18, 2.41]
1.1.2 Paroxetine vs. Placebo	1	91	Odds Ratio (M‐H, Random, 95% CI)	0.55 [0.24, 1.29]
1.2 Repetition of SH at final follow‐up (by NGA class)	3	243	Odds Ratio (M‐H, Random, 95% CI)	0.75 [0.42, 1.35]
1.2.1 Mianserin vs. Placebo	2	95	Odds Ratio (M‐H, Random, 95% CI)	1.07 [0.39, 2.99]
1.2.2 Nomifensine vs. Placebo	1	57	Odds Ratio (M‐H, Random, 95% CI)	0.81 [0.17, 3.81]
1.2.3 Paroxetine vs. Placebo	1	91	Odds Ratio (M‐H, Random, 95% CI)	0.55 [0.24, 1.29]
1.3 Treatment acceptability	2	205	Odds Ratio (M‐H, Random, 95% CI)	0.70 [0.29, 1.71]