Arbogast 2016.

Study characteristics
Methods	A 13.5‐month prospective cluster‐RCT executed with alcohol‐based hand sanitiser in strategic workplace locations and personal use (intervention group) and brief hand hygiene education (both groups). 4 years of retrospective data were collected for all participants.
Participants	Data for a total of 1183 participants were analysed (intervention group = 525, control group = 607). Inclusion criteria: all employees at 3 facilities who were 18 years of age or older, were enrolled in the company health insurance coverage, did not transfer between sites, and worked onsite full time (≥ 32 hours) were eligible for the study Exclusion criteria: not reported
Interventions	Alcohol‐based hand sanitiser in strategic workplace locations and personal use (intervention group) and brief hand hygiene education (both groups). See Table 4 for details.
Outcomes	(1) The number of healthcare insurance claims, for a defined set of preventable illnesses, per participant per year, and (2) absenteeism, defined as the number of sick episodes per participant per year Claims based on ICD‐9 codes No safety outcomes reported.
Notes	Industry funded; only 2 clusters (1 per group) included, hence study data not included in meta‐analysis.
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Unclear risk	No details provided.
Allocation concealment (selection bias)	Unclear risk	No details provided.
Blinding of participants and personnel (performance bias) All outcomes	High risk	Unblinded study
Blinding of outcome assessment (detection bias) All outcomes	High risk	Unblinded study
Incomplete outcome data (attrition bias) All outcomes	Low risk	Attrition minimal and similar in 2 groups
Selective reporting (reporting bias)	Unclear risk	No protocol available