Comparison 4. Corticosteroids versus placebo or no treatment ‐ hypertension syndrome versus all other trials.

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
4.1 Perinatal deaths ‐ hypertension syndrome vs other trials	14	9833	Risk Ratio (M‐H, Fixed, 95% CI)	0.85 [0.77, 0.93]
4.1.1 Hypertension syndrome	2	313	Risk Ratio (M‐H, Fixed, 95% CI)	0.83 [0.57, 1.20]
4.1.2 No hypertension syndrome or hypertension syndromes excluded	1	1123	Risk Ratio (M‐H, Fixed, 95% CI)	0.86 [0.67, 1.10]
4.1.3 Hypertension not reported separately	12	8397	Risk Ratio (M‐H, Fixed, 95% CI)	0.85 [0.76, 0.94]
4.2 Neonatal deaths ‐ hypertension syndrome vs other trials	22	10609	Risk Ratio (M‐H, Fixed, 95% CI)	0.78 [0.70, 0.87]
4.2.1 Hypertension syndrome	2	313	Risk Ratio (M‐H, Fixed, 95% CI)	0.48 [0.28, 0.83]
4.2.2 No hypertension syndrome or hypertension syndromes excluded	1	1123	Risk Ratio (M‐H, Fixed, 95% CI)	0.90 [0.65, 1.25]
4.2.3 Hypertension not reported separately	20	9173	Risk Ratio (M‐H, Fixed, 95% CI)	0.78 [0.70, 0.88]
4.3 Fetal deaths ‐ hypertension syndrome vs other trials	14	9833	Risk Ratio (M‐H, Fixed, 95% CI)	1.01 [0.83, 1.22]
4.3.1 Women with hypertension syndrome	3	331	Risk Ratio (M‐H, Fixed, 95% CI)	1.73 [0.91, 3.28]
4.3.2 No hypertension syndrome or hypertension syndromes excluded	2	1373	Risk Ratio (M‐H, Fixed, 95% CI)	0.74 [0.49, 1.12]
4.3.3 Hypertension not reported separately	11	8129	Risk Ratio (M‐H, Fixed, 95% CI)	1.04 [0.83, 1.30]
4.4 Respiratory distress syndrome ‐ hypertension syndrome vs other trials	26	11183	Risk Ratio (M‐H, Fixed, 95% CI)	0.71 [0.65, 0.78]
4.4.1 Hypertension syndrome	5	418	Risk Ratio (M‐H, Fixed, 95% CI)	0.48 [0.34, 0.69]
4.4.2 No hypertension syndrome or hypertension syndromes excluded	7	2511	Risk Ratio (M‐H, Fixed, 95% CI)	0.60 [0.48, 0.74]
4.4.3 Hypertension not reported separately	19	8254	Risk Ratio (M‐H, Fixed, 95% CI)	0.78 [0.70, 0.87]