Table 3.
Tumors with structures that mimic ependymoblastic rosettes. Abbreviations: EMA = epithelial membrane antigen; GFAP = glial fibrillary acidic protein; ND = not done; NeuN = neuronal nuclei antigen; PNET = primitive neuroectodermal tumor.
Case | Age (months) | Sex | Location | Synaptophysin | Neurofilament | NeuN | GFAP | EMA | Ki‐67 | Diagnosis |
---|---|---|---|---|---|---|---|---|---|---|
12 | 32 | Male | Posterior fossa | ND | − | ND | + | Scattered + dot‐like cytoplasmic | Up to 12% | PNET |
13 | 45 | Female | Temporal lobe | − | Weakly + | ND | Scattered cells | − | ND | PNET |
14 | 46 | Female | Parieto‐occipital | + | ND | ND | Scattered cells | ND | Variable, up to 80% | PNET |