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. 2021 Apr 16;2021(4):CD010682. doi: 10.1002/14651858.CD010682.pub3

Hovorka 2000.

Study characteristics
Methods A single‐centre, non‐randomised, uncontrolled, prospective before and after study (Prague)
Baseline period: 2 months
Treatment period: 8 weeks
Participants 43 people with focal epilepsy exceeding 15 points on the Hamilton Rating Scale for Depression (HAMD) 21 scale for depression
35 females and 8 males
Aged 21 to 49 years: mean 33.2 years
Interventions Citalopram at a flexible dose; the average dose was 19.3 mg ± 2.6 mg at the end of the first month, 22.62 mg ± 8.3 mg at the end of the second month
Outcomes 1) Seizure frequency
2) Depressive symptoms measured by the HAMD‐21
3) Adverse effects
Notes No dropouts and no exclusions from the analysis