Hovorka 2000.
Study characteristics | ||
Methods | A single‐centre, non‐randomised, uncontrolled, prospective before and after study (Prague) Baseline period: 2 months Treatment period: 8 weeks | |
Participants | 43 people with focal epilepsy exceeding 15 points on the Hamilton Rating Scale for Depression (HAMD) 21 scale for depression 35 females and 8 males Aged 21 to 49 years: mean 33.2 years | |
Interventions | Citalopram at a flexible dose; the average dose was 19.3 mg ± 2.6 mg at the end of the first month, 22.62 mg ± 8.3 mg at the end of the second month | |
Outcomes | 1) Seizure frequency 2) Depressive symptoms measured by the HAMD‐21 3) Adverse effects |
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Notes | No dropouts and no exclusions from the analysis |