Kanner 2000.

Study characteristics
Methods	A single‐centre, non‐randomised, uncontrolled, prospective before and after study (USA) Baseline period: not reported Treatment period: mean 10.3 months (0.2 to 38 months)
Participants	100 people with focal epilepsy, with depressive or obsessive compulsive disorder 51 males and 49 females Aged 6 to 62 years: mean 29.9 years
Interventions	Sertraline, mean dose of 108 mg ± 56.9 mg per day
Outcomes	1) Improvement in depressive symptoms 2) Seizure frequency 3) Adverse effects
Notes	18 people withdrew due to adverse effects; all included in analysis